Amitava Dasgupta, Ph.D.

Professional Background

Amitava Dasgupta received his Ph. D in chemistry from Stanford University and completed his fellowship training in Clinical Chemistry from the Department of Laboratory Medicine at the University of Washington School of Medicine at Seattle. He is board certified in both Toxicology and Clinical Chemistry by the American Board of Clinical Chemistry. Currently, he is a tenured Full Professor of Pathology and Laboratory Medicine at the University of Kansas Medical Center and Director of Clinical Laboratories at the University of Kansas Hospital. He has published 240 scientific papers, wrote many invited review articles and abstracts edited, co-edited, co-authored and wrote a total of 20 books. He is on the Editorial Board of five journals. He is the recipient of 2009 Irvine Sunshine Award from the International Association for Therapeutic Drug Monitoring and Clinical Toxicology (IATDMCT) for outstanding contribution in clinical toxicology and in 2010 he received AACC Outstanding contribution to education Award.

• BSc, Bachelor of Science, University of Calcutta, Calcutta
• MS, Analytical Chemistry, University of Georgia, Athens, Georgia
• PhD, Organic Chemistry, University of Washington
• Post Doctoral Fellowship, Clinical Chemistry, University of Washington

• American Association for Clinical Chemistry, Vice President, 2007 - 2009
• American Association for Clinical Chemistry, Member, 1999 - 2002

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Research

Overview

He has published 240 scientific papers and has a h-index of 44. His research interest is in the field of therapeutic drug monitoring and toxicology. He has published papers on interference of various Chinese and herbal supplements on therapeutic drug monitoring of digoxin and also on clinically significant drug-herb interactions. In earlier part of his career he focused on clinical utility of monitoring unbound (free drug concentrations). he is on the editorial board of five journals including Archives of Pathology and Laboratory Medicine and Therapeutic Drug Monitoring.

• Dasgupta, A, Handy, B, Datta, P. 2000. Mathematical models to calculate fosphenytoin concentrations in the presence of phenytoin using phenytoin immunoassays and alkaline phosphatase . American Journal of Clinical Pathology (113), 87-92
• Dasgupta, A, Biddle, D, Wells, A, Datta, D. 2000. Positive and negative interference of oriental medicine Chan SU in serum digoxin measurement . American Journal of Clinical Pathology (114), 174-179
• Dasgupta, A, Galvan-Neto, T, Wells, A, Olson, M, Actor, J. 2001. Digitoxin-like immunoreactivity in sera of mice after feeding with Chinese medicine Chan Su: Study of protein binding of Chan Su in normal sera, uremic sera and sera from patients with liver disease. Clnica Chimica Acta (305), 175-179
• Dasgupta, A, Wahed, A, Wells, A. 2002. Rapid spot tests for detecting adulterants in urine specimens submitted for drug testing. American Journal of Clinical Pathology (117), 325-329
• Dasgupta, A, Wahed, A, Culton, L, Olsen, M, Wells, A, Actor, J. 2002. Activated charcoal is more effective than equilibrium dialysis in removing Chinese medicines Chan Su and Danshen from serum and activated charcoal also prevents further absorption of these agents from G.I. tract in mice: Monitoring the effect in clinical laboratory by measuring digoxin activity in serum. . Clinica Chimica Acta (324), 51-59
• Dasgupta, A, Datta, P. 2004. Detection of oleander toxicity using digoxin immunoassays: Five assays compared. Therapeutic Drug Monitoring (26), 658-663
• Rodriguez, M., E, Poindexter, B., J, Bick, R., J, Dasgupta, A. 2008. A comparision of the effects of commercially available hawthorn preparations on calcium transients of isolated cardiomyocyte. Journal of Medicinal Food (11), 680-686
• McMillin, G., A, Juenke, J., M, Tso, G, Dasgupta, A. 2010. Estimation of Carbamazepine and Carbamazepine 10, 11-Epoxide Concentrations in Plasma Using Mathematical Equations Generated with Two Carbamazepine Immunoassays. American Journal of Clinical Pathology (133), 728-736
• Dixon, R., B, Dasgupta, A. 2015. Zinc sulfate, a recently introduced urinary adulterant can invalidate urine cotinine test using immunoassay but has less effect on liquid chromatography combined with tandem mass spectrometry based test . Therapeutic Drug Monitoring (37), 681-684
• Dasgupta, A, Khalil, S, Paddock, T, Wahed, A. 2022. Bimodal negative interference of biotin in Roche IL-6 immunoassay. Annals of Clinical and Laboratory Science (52), 161-163